Red cells production (erythropoeisis) sites in bone marrow of a normal subject. Maximum intensity projection image after OSEM (left) and FBKP (right) reconstructions at equivalent spatial resolution. Wholebody scan data were acquired in 2D-mode (septa extended) on an ECAT Exact HR PET scanner after injection of 3 mCi of 52-Fe. Filtered backprojection images were reconstructed with a Hanning filter and an isotropic spatial resolution of 8 mm. Sinograms corrected for attenuation and scatter, were first smoothed with an isotropic gaussian filter with 8 mm (FWHM) prior to reconstruction with OSEM and 4 iterations. (by courtesy of M. Lonneux, F. Jamar and C. Michel, Positron Tomography Laboratory, UCL Belgium)